Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice.pdf

所属栏目:精神病学

【日期】:2024-06-05
【关键词】:Alzheimeru0027s disease;amyloid-β;APP/PS1 mice;cerebrovascular endothelial cells;cognitive deficits;gamma-glutamyl transferase 5;neurovascular unit;nuclear factor-kappa B;synaptic plasticity;β-site AP

【摘要】:In patients with Alzheimeru0027s disease, gamma-glutamyl transferase 5(GGT5) expression has been observed to be downregulated in cerebrovascular endothelial cells. However, the functional role o...


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